Can You Take Nyquil During the Day? Should You?

logo by Editorial Staff | Updated on June 22nd, 2022

Nyquil is a nighttime cold medicine. It’s not meant for daytime use. However, many people are accustomed to taking it daily because they find it helps them feel better faster. The idea of taking Nyquil during the day may be slightly alarming, as it’s not advised by the manufacturer and can have dangerous side effects if taken at the wrong time.


However, if you insist on taking Nyquil during the day, there are some things you should know before proceeding further. Taking Nyquil in the daytime has its pros and cons. The drug is not intended to be used this way, so you must understand all the details before making that choice.

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Can I take NyQuil during the day if you don’t have DayQuil?

You can use NyQuil during the day if you know it can cause fatigue and drowsiness.

NyQuil includes doxylamine, a sedative that will make you sleepy. So, while you can take NyQuil throughout the day, it will make you sleepy.

If you use NyQuil throughout the day, avoid undertaking tasks that need mental alertness (examples: driving and operating heavy machinery). A single dosage of NyQuil will keep you up for 4 to 6 hours.

Continue reading to find out if NyQuil may be used throughout the day. Also, learn more about NyQuil dose, side effects, and other topics.

Can you take NyQuil during the day?

NyQuil is a cough and cold drug designed to be used at night. NyQuil may be used during the day, although the sedative effects of its components will make you sleepy.

Because it might produce sleepiness and drowsiness, it is best taken at night or while you are at home relaxing. If you use NyQuil during the day, avoid tasks needing mental alert, like driving.

Other cough and cold drugs do not produce drowsiness and are intended to be used throughout the day. DayQuil, another Vicks product, is one of them. Acetaminophen, dextromethorphan, and phenylephrine are the active components of DayQuil.

Keep in mind that NyQuil was designed as a nighttime multi-symptom relief medicine.

What Exactly Is NyQuil?

Vicks manufactures and sells NyQuil to treat cough, cold, and flu symptoms such as the following:

Fever, headache, cough, nasal congestion, sore throat, and mild body pains are all flu symptoms.

Because it includes chemicals that might produce drowsiness, it was designed to be taken at night.

NyQuil is an over-the-counter medication that does not require a doctor’s prescription. It is typically safe for adults and children over six to use.

What is in NyQuil That Makes You Sleep?

Ingredients in Use

NyQuil’s active components are as follows:

Dextromethorphan, acetaminophen, and doxylamine

Dextromethorphan is a cough suppressant, while acetaminophen reduces fever and discomfort. Finally, Doxylamine acts as an antihistamine. The component in NyQuil that makes you sleepy is doxylamine.

Doxylamine, like the antihistamine Benadryl (diphenhydramine), is a first-generation antihistamine that induces sleepiness and sedation. Each NyQuil dosage will last four to six hours.

Almost all antihistamines produce sleepiness, although they provide relief and comfort for various cold symptoms. NyQuil contains doxylamine, which relieves itchy and watery eyes.

Antihistamines have drying qualities. Thus they can help with post-nasal drip and a runny nose.

Doxylamine is frequently used as a sleep aid on its own. That’s how calming it is. Doxylamine is an active component in certain sleep aids.

Alcohol (10% by volume) is also listed as a component in NyQuil. This is because drowsiness can also be caused by alcohol.

It’s worth noting that NyQuil is also available in an alcohol-free formulation. This kind employs a different antihistamine. It substitutes chlorpheniramine for doxylamine.

Chlorpheniramine, like doxylamine, can produce drowsiness, although it is less sedating. It, like Doxylamine, treats runny noses and watery or red eyes.

What Happens During the Day When You Take NyQuil?

The effects of each NyQuil dosage will last between 4 and 6 hours. NyQuil was designed to be administered at night since it includes an antihistamine, which causes sleepiness and fatigue. If used during the day, it may impair your mental attentiveness.

Is it okay to use NyQuil throughout the day? It’s OK to take NyQuil if you’re staying at home and relaxing for the day. However, it is advised to avoid taking NyQuil throughout the day if you drive or use heavy machinery.

How Should NyQuil Be Taken?

It would help if you always took NyQuil precisely as instructed on the label or as prescribed by your doctor. In addition, it would help if you did not use it for any longer than is suggested. Cough, cold, and flu drugs are frequently taken for a brief time until your symptoms subside.

  1. Do Not Exceed the Suggested Dosage

Do not take more than the suggested amount. NyQuil includes acetaminophen, which can cause liver damage or even death if used in excess.

  1. If the symptoms do not improve, contact your doctor.

If your symptoms do not improve or clear up after two days, or if you still have a sore throat, discontinue using NyQuil and consult your doctor. Repeat the procedure if you still have a fever, rash, nausea, and vomiting. You may require other drugs or therapy.

  1. Make use of a Measuring Spoon or Cup.

Use a measuring spoon or medication cup to achieve the correct dosage of NyQuil liquid preparation. You can get one from your pharmacist.

  1. Tell your doctor that you took NyQuil before surgery or a test.

If you’re planning to have a medical test or have surgery, tell your surgeon or doctor that you’ve taken NyQuil in the last few days.

What Happens If I Don’t Take My NyQuil?

NyQuil is a prescription-only medication. Therefore, you can use NyQuil without following a dosage plan. However, if you are on a dosage regimen for NyQuil and miss a dose, you must still take it.

If the missed dosage is too close to the following dose, you should skip it and continue with the planned doses. Do not double the following dosage or take more medicine to compensate for the missing dose.

What Happens If I Take Too Much NyQuil?

NyQuil includes acetaminophen, and an acetaminophen overdose can be dangerous. If you overdose on NyQuil, get immediate medical treatment.

Acetaminophen overdose symptoms include nausea, lack of appetite, stomach discomfort, sweating, and vomiting. You may also notice dark-colored urine and skin and ocular jaundice.

What should I avoid while on NyQuil?

Before taking any cold or allergy medication, please consult with your doctor to ensure that it is safe for you to use. Acetaminophen is present in several multi-symptom medications. Always read the product label to find precisely what is in the medication.

  1. Do Not Increase the Dosage

Take care not to double the doses of any medications by taking them simultaneously. It should be noted that consuming too much acetaminophen might result in a lethal overdose.

  1. Do Not Consume Alcoholic Beverages

Don’t consume alcoholic drinks if you’re taking acetaminophen-containing medications. You may raise your risk of liver damage by doing so.

  1. Avoid activities that need mental alertness.

NyQuil may induce blurred vision and impair mental attentiveness. Therefore, avoid driving, using heavy machinery, and performing tasks that need mental alertness.

Possible NyQuil Adverse Reactions (Next Day)

There will be adverse effects with all drugs. If you have hives or any other response, such as trouble breathing, or swelling of the face, tongue, throat, and lips, seek emergency medical attention immediately.

Acetaminophen is included in NyQuil. In rare situations, acetaminophen can produce a potentially deadly skin response. This response can occur whenever you take acetaminophen, even if you have previously taken it.

If you experience skin rashes or redness with blisters, get emergency medical attention immediately. If you experience this response, you should discontinue all acetaminophen-containing medications.

These NyQuil (next day) adverse effects are possible but unusual with taking acetaminophen:

  • Seizures
  • Extensive headaches
  • Uneven and erratic heartbeat
  • Tremor
  • Confusion and hallucinations
  • Severe vertigo
  • Breathing is shallow and slow.
  • Easily bruising, unusual bleeding
  • Upper stomach discomfort, nausea, and appetite loss
  • Dark urine, little or no pee, and clay-colored stools

The following are the most common acetaminophen side effects:

  • Headache
  • Insomnia
  • Constipation or diarrhea
  • Drowsiness and dizziness
  • A minor skin rash

The list of acetaminophen side effects provided above is not exhaustive. Inquire with your doctor about using acetaminophen and the potential adverse effects.

What You Should Know Before Taking NyQuil

If you have liver disease, tell your doctor before using any acetaminophen-containing medication. In addition, notify your doctor if you consume three or more alcoholic beverages daily.

Do not use NyQuil if you have taken any MAO (monoamine oxidase) inhibitor in the previous 14 days. NyQuil and MAOs can have drug interactions. Isocarboxazid, phenelzine, furazolidone, linezolid, tranylcypromine, and rasagiline are some MAO inhibitors.

Do not take NyQuil if you have ever had an allergic reaction to acetaminophen, doxylamine, or dextromethorphan.

If you have any of the following medical problems, see your doctor before using NyQuil:

  • Asthma,
  • COPD, cough with thick mucus, a cough induced by smoking, chronic bronchitis
  • You have a clog in your intestines and a blockage in your stomach.
  • Illness of the liver
  • Diabetic kidney disease
  • Prostate issues include an enlarged prostate
  • Urination issues
  • Glaucoma
  • If you are using potassium supplements,

It is unknown if the active components in NyQuil can damage an unborn fetus. However, if pregnant, see your doctor before taking any cough and cold medications.

Cough and cold medications can enter breastfeeding. As a result, if you are a nursing mother, you should avoid using NyQuil. According to research, most antihistamines can reduce breast milk production.

Before giving NyQuil to a kid, consult a doctor. Unfortunately, some fatalities have occurred due to the overuse of some cold medications in very young children.

The effects may be exacerbated if you use NyQuil alongside other drugs that might induce drowsiness or impede your breathing. Inform your doctor if you want to use NyQuil while taking a sleeping pill, anti-anxiety or anti-depression medicine, or a pain reliever.

Is it OK to use NyQuil to help with sleep?

More research is being done to determine the safety and efficacy of NyQuil as a sleeping aid.

According to several research, first-generation antihistamines (particularly doxylamine succinate) can be used to alleviate insomnia in the short term.

However, there hasn’t been enough research to indicate that doxylamine is a safe and effective sleep aid.

According to research, doxylamine can induce the following adverse effects:

  • Vision hazard
  • Headache
  • Nausea
  • Mouth, throat, and nose dryness
  • Restlessness
  • Respiratory system congestion

Doxylamine tolerance can also be established fast, according to research. This implies that if you take it too frequently, the sedative effect of doxylamine may be reduced.

NyQuil contains other chemicals that are not required for usage as a sleeping aid. If you genuinely require a sleep aid, it is preferable and safer to utilize an over-the-counter sleep medication to treat insomnia. NyQuil was designed primarily to treat coughs, colds, and flu symptoms.

Keep your NyQuil container or gel caps out of the reach of youngsters, as you would any other medication. Instead, use the medication exclusively for the intended purpose and follow the dose directions.

Is it possible to become addicted to NyQuil?

Even with frequent usage, NyQuil has no significant dangers when taken as advised. However, it is preferable to quit taking it to induce sleep. So, while taking NyQuil as intended is considered safe, taking it in ways that are not advised can be hazardous.

Some may discover that the average amount they take does not provide the same impact as prolonged use. Instead, they may take longer to fall asleep or sleep for a shorter period. Taking higher or more frequent dosages to have the same effect typically indicates that the body has built a tolerance to the drug and is likely to have developed dependency and addiction.

As with any medication, this is a serious matter that should be dealt with. Withdrawal symptoms may develop, and the user should seek medical or mental health treatment.

Conclusion – can you take NyQuil during the day?

NyQuil can be taken during the day. NyQuil, on the other hand, contains doxylamine, which causes weariness and sleepiness. This is why taking NyQuil at night is preferable.

If you use NyQuil during the day, avoid tasks needing mental alert, like driving.

NyQuil is a cough and cold medication that should be used at night since it might make you tired and weary. However, this does not preclude you from taking it during the day.

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Editorial Staff

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