Combining celecoxib and ibuprofen may make the side effects of these drugs worse. An increased risk of severe gastrointestinal toxicity may be present, such as ulceration, inflammation, perforation, and bleeding.
Each medication’s risks are influenced by its dosage and treatment length.
If you have any concerns or questions, consult your doctor. To use both medications safely, you could require more frequent monitoring or a dose adjustment, or your doctor might be able to prescribe substitutes that don’t interact.
Given that they function differently, taking celecoxib alongside paracetamol is safe.
What is Celebrex?
Nonsteroidal anti-inflammatory drugs, NSAIDs, are a class of medications that includes Celebrex. A class of drugs is a collection of drugs with similar mechanisms of action. Celecoxib is the active component in Celebrex.
Celebrex is available as a capsule for ingestion. You can alternatively break open the capsule and ingest the contents by sprinkling them on a spoonful of applesauce.
The four strengths offered are 50 milligrams, 100 milligrams, 200 milligrams, and 400 milligrams of Celebrex.
Celebrex is a name-brand drug that requires a prescription. It has FDA approval allowing it to treat the following conditions* by easing pain and lowering inflammation (swelling and damage):
- Acute short-term pain in adults
- Osteoarthritis (OA)
- Ankylosing spondylitis (a form of arthritis that impacts the spine)
- Rheumatoid arthritis (RA)
- JRA, or juvenile rheumatoid arthritis
- Primary dysmenorrhea (period pain or menstrual cramps)
Celebrex side effects
Side effects of Celebrex can range from mild to severe. Some of the most significant side effects that could happen when using Celebrex are listed below.
Consult your doctor or pharmacist for further details on Celebrex’s potential side effects. They can offer you advice on how to handle any uncomfortable side effects.
Mild side effects
Among Celebrex’s mild side effects are the following:
- Vomiting and nausea
- Indigestion/ upset stomach
- Abdominal pain
- Swelling of the hands and feet
- Weight gain
- Sinusitis (inflammation of the sinus)
- Upper respiratory infection, like the common cold
Most of these side effects might disappear in a few days or weeks. However, consult your doctor or pharmacist if they worsen or persist.
Serious side effects
Celebrex rarely has severe side effects, but they can happen. Immediately contact your doctor if you have any severe side effects. If you suspect you have a medical emergency or that your symptoms are life-threatening, dial 911 or your local emergency number.
- Heart attack or chest pain
- Stroke. Symptoms can include:
- slurred speech
- sagging/drooping on the side of the face
- abrupt weakness in one area or side of the body
- blurred vision
- unexpected dizziness or difficulty walking
- Extremely severe headaches with no additional symptoms
- Elevated blood pressure
- Edema. Symptoms could include:
- swelling in your hands, feet, arms, and legs
- sudden weight gain
- Allergic reactions. Symptoms can be:
- itching and hives
- swelling in your throat or face
- Stomach and intestinal ulcers and bleeding. Possible symptoms are:
- blood in urine
- bloody stools
- stools that are dark and sticky
- Reactions on the skin, such as a rash or blisters
- Liver issues. The scleras (whites of your eyes) or your skin may turn yellow as a symptom.
- Asthma flare-ups
What is ibuprofen?
NSAIDs, such as ibuprofen, treat inflammation. Ibuprofen lowers hormones that lead to pain and inflammation in the body.
Ibuprofen relieves pain or inflammation caused by various ailments, including toothache, headache, menstrual cramps, back pain, arthritis, and minor injuries. It is also used to lower fever.
Adults and children up to 6 months old can use ibuprofen.
Ibuprofen should be taken as instructed on the label or by your doctor. The lowest dose that can effectively treat your illness should be used.
Your intestines or stomach can become damaged by an ibuprofen overdose. Adults should not take more ibuprofen than 800 milligrams per dose or 3200 mg daily (4 doses maximum).
Their age and weight determine the dosage for a child. Make sure to carefully follow the dosage recommendations for your child’s age and weight that come with children’s ibuprofen. If you have any questions, see a physician or a pharmacist.
Ibuprofen side effects
If you experience allergic reaction symptoms on ibuprofen (hives, trouble breathing, swelling in your face or throat), or a serious skin reaction, seek emergency medical attention (fever, burning eyes, sore throat, skin pain, purple or red skin rash with blistering and peeling).
If you encounter any of the following, stop using this medication and contact your doctor right away:
- Fast weight gain or swelling
- Alterations to your vision.
- Shortness of breath (even with mild exertion).
- A skin rash, regardless of how minor
- Bloody or tarry stools, bloody coughing fits, or vomit resembling coffee grounds are stomach bleeding symptoms.
- Anemia (reduced red blood cells) is characterized by pale skin, dizziness or shortness of breath, a rapid heartbeat, and difficulty focusing.
- Kidney issues: Symptoms include little to no urination, difficult or painful urination, ankle or foot edema, and fatigue or shortness of breath.
- Liver issues: Symptoms include fatigue, flu-like symptoms, nausea, upper stomach pain, itching, a lack of appetite, clay-colored stools, dark urine, and jaundice (yellowing of the skin or eyes).
Ibuprofen side effects commonly include:
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