Vicodin is a prescription medication used to treat pain. It’s a combination of hydrocodone and acetaminophen. Hydrocodone is an opioid pain reliever, and acetaminophen is a non-opioid pain reliever. Vicodin is available in tablet form and is usually taken orally. The effects of Vicodin can last anywhere from 4 to 6 hours.
Table Of Contents
−- How Long Does Vicodin Last
- What pain does Vicodin relieve?
- The half-life of Vicodin
- What is the peak time for Vicodin?
- Why the length of time Vicodin lasts matters
- How to know if your Vicodin is still working
- When to take another dose of Vicodin
- How to make Vicodin last longer
- What to do if you think your Vicodin has stopped working
- How many mg of Vicodin a day?
How Long Does Vicodin Last
Vicodin is a pain reliever that contains hydrocodone and acetaminophen. It is typically prescribed to relieve moderate to severe pain. The effects of Vicodin typically wear off after four to six hours. However, Vicodin can be detected in drug tests for up to 24 hours after use.

What pain does Vicodin relieve?
Vicodin is a prescription medication that is dispensed to treat moderate-to-severe pain. The active ingredients in Vicodin are acetaminophen and hydrocodone. These work together to relieve pain for approximately four hours. However, Vicodin can remain active in the bloodstream for up to 12 hours.
The half-life of Vicodin
Vicodin has a half-life of about four hours in healthy adults, making the five half-lives time frame 20 hours. This means that someone who is healthy and takes a standard dose of Vicodin can expect the drug to be completely out of their system within 20 hours.
What is the peak time for Vicodin?
Vicodin usually takes about an hour to start working. The effects of Vicodin peak in the bloodstream around 1.3 hours after taking the medication. For people with Vicodin addiction, withdrawal symptoms typically begin about 6-12 hours after their last dose.
Why the length of time Vicodin lasts matters
The length of time Vicodin lasts in the body is important for several reasons. First, Vicodin is a powerful pain reliever and can be helpful for people who are in pain. However, it is also a drug that can be abused, and people who use it regularly may experience withdrawal symptoms if they try to stop it. Additionally, traces of Vicodin can stay in the body for days after the last dose, so it is important to be aware of this if you are taking other medications.
How to know if your Vicodin is still working
If you are taking Vicodin, it is important to monitor how well the medication works. To do this, you can keep track of your pain levels and how often you need to take the medication. You should also let your doctor know if you experience any side effects from the Vicodin.
When to take another dose of Vicodin
Adults should take one or two capsules of Vicodin every four to six hours as needed for pain relief. Your doctor may increase your dosage as needed, but the maximum recommended dose is eight daily capsules. You should not take Vicodin for more than five days in a row without talking to your doctor. Taking this medication with alcohol or other drugs that can cause drowsiness can lead to serious side effects, including death.
How to make Vicodin last longer
The length of time Vicodin stays in your system depends on several factors, including age, genetics, and frequency of use. The average half-life for Vicodin is four hours, which means it can be detected in urine for up to two days after use. However, traces of the drug may still be present in the body for up to 36 hours.
What to do if you think your Vicodin has stopped working
If you think your Vicodin has stopped working, talk to your healthcare provider immediately. Do not change the dosage without talking to your healthcare provider. Your doctor must check your progress while using this medicine. If you have an opioid addiction, call the U.S. Substance Abuse and Mental Health Services Administration’s National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area.
How many mg of Vicodin a day?
The typical adult dosage for pain relief is one to two tablets every four to six hours. The daily dose should not exceed eight tablets. The typical adult dosage of VICODIN ES 7.5 mg/750 mg is one tablet every four to six hours as needed for pain. The maximum recommended daily dosage is five tablets.

Editorial Staff
Our writers, editors, content managers, and SEO specialist. We all take part in crafting amazing articles. We spend hours ensuring that each article is based on facts, researched, and thorough. You'll never want to click the back button to look for more answers other than here!