What Are the Risks of Using Xanax and Advil PM or Ibuprofen PM Together?

logo by Editorial Staff | Posted on November 16th, 2022

Ibuprofen and diphenhydramine are both ingredients in the combination drug Advil PM. Diphenhydramine, an antihistamine, can help with allergy symptoms but can also make you extremely sleepy.

Although some people can take Advil PM safely, Xanax shouldn’t be used with it. This is because the combination increases the likelihood of adverse effects like sleepiness, dizziness, disorientation, and attention deficit issues.

xanax and advil pm

Additionally, coordination, reasoning, and judgment can be impacted by combining Xanax and Advil PM. Older folks are in significantly greater danger. If you use Xanax and Advil PM simultaneously, stay away from anything that requires mental alertness.

What is Xanax?

Alprazolam, the active ingredient in Xanax, is frequently used to treat panic disorders and anxiety. Xanax is a member of the benzodiazepine drug class. Gamma-aminobutyric acid’s (GABA) activity is increased by the action of benzodiazepines on certain receptors in the brain, which has a calming effect.

There are three oral Xanax tablets: immediate-release, extended-release, and an orally disintegrating tablet. There is also an oral solution for alprazolam.

Alprazolam is a Schedule IV controlled substance, which means that compared to drugs in higher scheduling categories, it has a lesser risk of misuse or dependency. There are situations when abruptly discontinuing Xanax or drastically lowering your dosage might result in potentially fatal withdrawal symptoms.

What are the side effects of Xanax?

In addition to those listed below, there may be other side effects. A medical expert can provide you with advice on side effects. Consult your pharmacist or a doctor if you notice any other symptoms.

Like most drugs, Xanax can have both minor and major side effects. Most of the time, side effects start with treatment and disappear over time.

Common side effects

Listed below are some of the most typical side effects of alprazolam:

  • Dry mouth 
  • Unsteadiness or faintness
  • Memory issues 
  • Drowsiness
  • Headache
  • Difficulty focusing 
  • Constipation
  • Issues with sleep
  • Lack of enthusiasm 
  • Distorted vision
  • Alteration in appetite
  • Diarrhea 
  • Nausea or vomiting
  • Muscle tremors

If these side effects persist or worsen, speak with your doctor or pharmacist.

What is ibuprofen, and how can it be used?

Ibuprofen belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is frequently used for its capacity to reduce inflammation and relieve pain.

It may be taken up to three times daily after meals and is sold over the counter in tablets or capsules in quantities ranging from 200 to 400 mg.

Some people find that tablets that release the medication gradually over time are useful for nighttime pain management.

If you have rheumatoid arthritis or other inflammatory arthritis, you can get higher dosages of ibuprofen on a prescription.

You should speak with your doctor if ibuprofen isn’t providing enough pain relief or if you require pain treatment for an extended period. Your doctor may be able to prescribe a stronger NSAID or a drug combination that will be more efficient.

Ibuprofen side effects 

Ibuprofen’s typical side effects include the following:

  • Rash
  • Nausea 
  • Vomiting 
  • Abdominal and stomach pain
  • Heartburn
  • Headache
  • Ringing in the ears
  • Dizziness 
  • Swelling (edema) 
  • Retention of fluid
  • Skin peeling
  • Constipation 
  • Sun sensitivity (photosensitivity reactions)


Editorial Staff

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